1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th Edition. Washington, DC: American Psychiatric Association; 2013.
2. Smith MY, Redd WH, Peyser C, Vogl D. Posttraumatic stress disorder in cancer: a review. Psychooncology 1999;8:521–537. PMID:
10607985.
3. Tedstone JE, Tarrier N. Posttraumatic stress disorder following medical illness and treatment: a review. Clin Psychol Rev 2003;23:409–448. PMID:
12729679.
4. Pine DS, McClure EB. Clinical Features of Anxiety Disorders. In: Sadock BJ, Sadock VA, editor. Kaplan & Sadocks's Synopsis of Psychiatry: Behavioral Sciences, Clinical Psychiatry. 9th edition. Philadelphia: Lippincott Williams & Wilkins Publishing, 2003, p. 623–631.
5. Briere J, Elliott D. Prevalence, characteristics, and long-term sequelae of natural disaster exposure in the general population. J Trauma Stress 2000;13:661–679. PMID:
11109238.
6. Kokai M, Senta F, Naotaka S, Edwards G. Natural disaster and mental health in Asia. Psychiatry Clin Neurosci 2004;58:110–116. PMID:
15009813.
7. Başoğlu M, Şalcıoğlu E, Livanou M. Traumatic stress responses in earthquake survivors in Turkey. J Trauma Stress 2002;15:269–276. PMID:
12224798.
8. Lai TJ, Chang CM, Connor KM, Lee LC, Davidson JR. Full and partial PTSD among earthquake survivors in rural. J Psychiatr Res 2004;38:313–322. PMID:
15003437.
9. Aker AT. 1999 Marmara Earthquakes: a review of epidemiologic findings and community mental health policies. Turk Psikiyatri Derg 2006;17:204–212. PMID:
17004172.
10. Bremner JD. Does stress damage the brain? Biol Psychiatry 1999;45:797–805. PMID:
10202566.
11. Villarreal G, Petropoulos H, Hamilton DA, Rowland LM, Horan WP, Griego JA, et al. Proton magnetic resonance spectroscopy of the hippocampus and occipital white matter in PTSD: preliminary results. Can J Psychiatry 2002;47:666–670. PMID:
12355679.
12. Harvey BH, Oosthuizen F, Brand L, Wegener G, Stein DJ. Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors inrat hippocampus. Psychopharmacology (Berl) 2004;175:494–502. PMID:
15138761.
13. Su YA, Wu J, Zhang L, Zhang Q, Su DM, He P, et al. Dysregulated mitochondrial genes and networks with drug targets in postmortem brain ofpatients with posttraumatic stress disorder (PTSD) revealed by human mitochondria-focusedcDNA microarrays. Int J Biol Sci 2008;4:223–235. PMID:
18690294.
14. Zanaboni G, Dyne KM, Rossi A, Monafo V, Cetta G. Prolidase deficiency: biochemical study of erythrocyte and skin fibroblast prolidase activity in Italian patients. Haematologica 1994;79:13–18. PMID:
15378943.
15. Vural M, Camuzcuoglu H, Toy H, Aksoy N. Amniotic fluid prolidase activity and oxidative status in neural tube defects. Fetal Diagn Ther 2010;28:34–39. PMID:
20516661.
16. Palka JA, Phang JM. Prolidase activity in fibroblasts is regulated by interaction of extracellular matrix with cell surface integrin receptors. J Cell Biochem 1997;67:166–175. PMID:
9328822.
17. Berrier AL, Yamada KM. Cell-matrix adhesion. J Cell Physiol 2007;213:565–573. PMID:
17680633.
18. Hu CA, Phang JM, Valle D. Proline metabolism in health and disease. Preface. Amino Acids 2008;35:651–652. PMID:
18504525.
19. McRae PA, Porter BE. The perineuronal net component of the extracellular matrix in plasticity and epilepsy. Neurochem Int 2012;61:963–972. PMID:
22954428.
20. Selek S, Altindag A, Saracoglu G, Celik H, Aksoy N. Prolidase activity and its diagnostic performance in bipolar disorder. J Affect Disord 2011;129:84–86. PMID:
20888649.
21. Mandel H, Abeling N, Gutman A, Berant M, Scholten EG, Sheiman C, et al. Prolidase deficiency among an Israeli population: prenatal diagnosis in a genetic disorder with uncertain prognosis. Prenat Diagn 2000;20:927–929. PMID:
11113899.
22. Aslan M, Nazligul Y, Horoz M, Bolukbas C, Bolukbas FF, Aksoy N, et al. Serum prolidase activity and oxidative status in Helicobacter pylori infection. Clin Biochem 2007;40:37–40. PMID:
16999949.
23. Andreazza AC, Kauer-Sant'anna M, Frey BN, Bond DJ, Kapczinski F, Young LT, et al. Oxidative stress markers in bipolar disorder: a metaanalysis. J Affect Disord 2008;111:135–144. PMID:
18539338.
24. Cakmak A, Zeyrek D, Atas A, Celik H, Aksoy N, Erel O. Serum prolidase activity and oxidative status in patients with bronchial asthma. J Clin Lab Anal 2009;23:132–138. PMID:
19288447.
25. Cakmak A, Soker M, Koc A, Aksoy N. Prolidase activity and oxidative status in patients with thalassemia major. J Clin Lab Anal 2010;24:6–11. PMID:
20087956.
26. Jacquet H, Demily C, Houy E, Hecketsweiler B, Bou J, Raux G, et al. Hyperprolinemia is a risk factor for schizoaffective disorder. Mol Psychiatry 2004;10:479–485. PMID:
15494707.
27. Weathers FW, Litz BT, Herman DS, Jusca J, Keane TM. The PTSD Checklist: Reliability, Validity and Diagnostic Utility. San Antonio, TX: Paper presented at the annual meeting of the International Society for Traumatic Stress Studies; 1993.
28. Kocabaşoğlu N, Çorapcıoğlu ÖA, Yargıc Ï, Geyran P. The validity and safety of turkish "PTSD checkust - civilian versıon" (PCL-C) scale. New Symposium 2005;43:126–134.
29. Kocabaşoğlu N, Özdemir S. An overwiev of the rating scales used in posttraumatic stress disorder. New Symposium 2005;43:173–178.
30. Guy W. ECDEU Assessment Manual for Psychopharmacology. Revised US Dept Health, Education and Welfare publication (ADM). Rockville, MD: National Institude of Mental Health; 1976.
31. Knox D, Perrine SA, George SA, Galloway MP, Liberzon I. Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the ratmedial prefrontal cortex. Neurosci Lett 2010;480:16–20. PMID:
20546834.
32. Kitayama N, Vaccarino V, Kutner M, Weiss P, Bremner JD. Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a metaanalysis. J Affect Disord 2005;88:79–86. PMID:
16033700.
33. Fontella FU, Siqueira IR, Vasconcellos AP, Tabajara AS, Netto CA, Dalmaz C. Repeated restraint stress induces oxidative damage in rat hippocampus. Neurochem Res 2005;30:105–111. PMID:
15756938.
34. Burgess N. Spatial cognition and the brain. Ann N Y Acad Sci 2008;1124:77–97. PMID:
18400925.
35. Yildiz F, Ulak G, Erdeb BF, Gacar N. Anxolytic-like effects of 7-nitroindazole in the rat plus-maze test. Pharmacol Biochem Behav 2000;65:199–202. PMID:
10672969.
36. Uzbay T. Neurobiology of anxiety and depression. Clin Psychiatry 2004;(suppl 4):3–11.
37. dos Reis EA, de Oliveira LS, Lamers ML, Netto CA, Wyse AT. Arginine administration inhibits hippokampal Na(+), K(+)-ATPase activity and impairs retention of an inhibitory avoidance task in rats. Brain Res 2002;951:151–157. PMID:
12270492.
38. Almeida A, Heales SJR, Bolanos JP, Medina JM. Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion. Brain Res 1998;790:209–216. PMID:
9593899.
39. Vermetten E, Bremner JD. Circuits and systems in stress: applications to neurobiology and treatment in posttraumatic stress disorder. Depress Anxiety 2002;16:14–38. PMID:
12203669.
40. Colas D, Gharib A, Bezin L, Morales A, Guidon G, Cespuglio R, et al. Regional age-related changes in nöronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain. BMC Neurosci 2006;7:81PMID:
17184520.
41. Chambers RA, Bremner JD, Moghaddam B, Southwick SM, Charney DS, Krystal JH. Glutamate and post-traumatic stress disorder: towards a psychobiology of dissociation. Semin Clin Neuropsychiatry 1999;4:274–281. PMID:
10553033.
42. Elzinga BM, Bremner JD. Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)? J Affect Disord 2002;70:1–17. PMID:
12113915.
43. Heresco-Levy U, Kremer I, Javitt DC, Goichman R, Reshef A, Blanaru M, et al. Pilot-controlled trial of D-cycloserine for the treatment of post-traumatic stress disorder. Int J Neuropsychopharmacol 2002;5:301–307. PMID:
12466030.
44. Harvey BH, Bothma T, Nel A, Wegener G, Stein DJ. Involvement of the NMDA receptor, NO-Cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma. Hum Psychopharmacol 2005;20:367–373. PMID:
15912566.
45. Oosthuizen F, Wegener G, Harvey BH. Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model. Neuropsychiatr Dis Treat 2005;1:109–123. PMID:
18568056.
46. Padovan CM, Del Bel EA, Guimaraes FS. Behavioral effects in the elevated plus maze of an NMDA antagonist injected into the dorsal hippocampus: influence of restraint stress. Pharmacol Biochem Behav 2000;67:325–330. PMID:
11124397.
47. Heiberg IL, Wegener G, Rosenberg R. Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats. Behav Brain Res 2002;134:479–484. PMID:
12191834.
48. Volke V, Wegener G, Bourin M, Vasar E. Antidepressant- and anxiolyticlike effects of selective neuronal NOS inhibitor 1-(2-trifluorome thylphenyl)-imidazole (TRIM) in mice. Behav Brain Res 2003;140:141–147. PMID:
12644287.
49. Wegener G, Volke V, Harvey BH, Rosenberg R. Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity. Brain Res 2003;959:128–134. PMID:
12480166.
50. Ulak G, Mutlu O, Akar FY, Komşuoğlu FI, Tanyeri P, Erden BF. Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats. Pharmacol Biochem Behav 2008;90:563–568. PMID:
18565575.
51. Campos AC, Piorino EM, Ferreira FR, Guimaraes FS. Increased nitric oxide-mediated neurotransmission in the medial prefrontal cortex is associated with the long lasting anxiogenic-like effect of predator exposure. Behav Brain Res 2013;01 256:391–397. PMID:
23948217.
52. Rodwell VW. Metabolism of Proteins & Amino Acids, Biosynthesis of the Nutritionally Nonessential Amino Acids. In: Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA, editor. Harper's Illustrated Biochemistry. 28th Ed. China: McGraw-Hill Companies, 2009, p. 478–479.
53. Cohen SM, Nadler J. Proline-induced potentiation of glutamate transmission. Brain Res 1997;761:271–282. PMID:
9252026.
54. Nadler JV, Wang A, Hakim A. Toxicity of L-proline toward rat hippocampal neurons. Brain Res 1988;456:168–172. PMID:
3409032.
55. Delwing D, Bavaresco CS, Wannmacher CM, Wajner M, Dutra-Filho CS, Wyse AT. Proline induces oxidative stress in cerebral cortex of rats. Int J Dev Neurosci 2003;21:105–110. PMID:
12615086.
56. Arikanoglu A, Akil E, Varol S, Yucel Y, Yuksel H, Cevik MU, et al. Relationship of cognitive performance with prolidase and oxidative stress in Alzheimer disease. Neurol Sci 2013;34:2117–2121. PMID:
23479033.
57. Schroeter H, Boyd C, Spencer JP, Williams RJ, Cadenas E, Rice-Evans C. MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide. Neurobiol Aging 2002;23:861–880. PMID:
12392791.
58. Tsuruda T, Costello-Boerrigter LC, Burnett JC Jr. Matrix metalloproteinases: pathways of induction by bioactive molecules. Heart Fail Rev 2004;9:53–61. PMID:
14739768.
59. Surazynski A, Liu Y, Miltyk W, Phang JM. Nitric oxide regulates prolidase activity by serine/threonine phosphorylation. J Cell Biochem 2005;96:1086–1094. PMID:
16167338.
60. Nunoshiba T, deRojas-Walker T, Wishnok JS, Tannenbaum SR, Demple B. Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages. Proc Natl Acad Sci U S A 1993;90:9993–9997. PMID:
8234347.
61. Endo F, Matsuda I, Ogata A, Tanaka S. Human erythrocyte prolidase and prolidase deficieny. Pediatr Res 1982;16:227–231. PMID:
7063276.
62. Royce PM, Steinma B. Prolidase Deficiency. New York: Wiley-Liss; 1993.
63. Ceprnja M, Derek L, Unić A, Blazev M, Fistonić M, Kozarić-Kovacić D, et al. Oxidative stress markers in patients with post-traumatic stress disorder. Coll Antropol 2011;35:1155–1160. PMID:
22397253.
64. Tezcan E, Atmaca M, Kuloglu M, Ustundag B. Free radicals in patients with post-traumatic stress disorder. Eur Arch Psychiatry Clin Neurosci 2003;253:89–91. PMID:
12799747.
65. Gergerlioglu HS, Savas HA, Bulbul F, Selek S, Uz E, Yumru M. Changes in nitric oxidelevel and superoxide dismutase activity during antimanic treatment. Prog Neuropsychopharmacol Biol Psychiatry 2007;31:697–702. PMID:
17303295.
66. Savaş HA, Herken H, Yurekli M, Uz E, Tutkun H, Zoroğlu SS, et al. Possible role of nitricoxide and adrenomedullin in bipolar affective disorder. Neuropsychobiology 2002;45:57–61. PMID:
11893860.
67. Bahceci B, Bagcioglu E, Kokacya MH, Dilek AR, Bahceci I, Selek S. Prolidase activity and oxidative stress in patients with schizophrenia: A preliminary study. J Pak Med Assoc 2015;65:131–135. PMID:
25842545.
68. Javitt DC. Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamateinteractions. Int Rev Neurobiol 2007;78:69–108. PMID:
17349858.
69. Krystal JH, D'Souza DC, Mathalon D, Perry E, Belger A, Hoffman R. NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology (Berl) 2003;169:215–233. PMID:
12955285.
70. Yildiz A, Demirbag R, Yilmaz R, Gur M, Altiparmak IH, Akyol S, et al. The association of serum prolidase activity with the presence and severity of coronary arterydisease. Coron Artery Dis 2008;19:319–325. PMID:
18607169.