The MAKE Biomarker Discovery for Enhancing anTidepressant Treatment Effect and Response (MAKE BETTER) Study: Design and Methodology

Article information

Psychiatry Investig. 2019;16(10):791-792

Publication date (electronic) : 2019 October 16

doi : https://doi.org/10.30773/pi.2017.10.2.e1

Hee-Ju Kang ¹, Ju-Wan Kim ¹, Seon-Young Kim ², Sung-Wan Kim ¹, Hee-Young Shin ³, Myung-Geun Shin ⁴, Jae-Min Kim ¹

¹Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea

²Mental Health Clinic, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea

³Department of Biomedical Science, Chonnam National University Medical School, and Clinical Trial Center, Chonnam National University Hospital, Gwangju, Republic of Korea

⁴Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea

This corrects the article "The MAKE Biomarker Discovery for Enhancing anTidepressant Treatment Effect and Response Study: Design and Methodology" in Volume 15 on page 538.

Psychiatry Investig 2018;15(5):538-545

https://doi.org/10.30773/pi.2017.10.2

In the original publication, the schedule of follow-up assessment was incorrect. The description in the study design and recruitment of the Method section has been changed as follows: Eligible patients with depressive disorders who agreed to participate in the MAKE BETTER study were approached for follow-up assessments at 1, 2, 3, 6 and 9 weeks; 3 months; and every 3 months thereafter up to 2 years to determine the short- and long-term treatment outcomes and clinical course of their depressive disorder. Accordingly, the Table 2 has been changed as follows. The authors sincerely regret these missing errors.

Table 2.

Schedule of assessment for MAKE BETTER study

Article information Continued

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Table 2.

Schedule of assessment for MAKE BETTER study

			Base-line	1 weeks	2 weeks	3 weeks	6 weeks	9 weeks	3 Month	6 Month	9 Month	12 Month	15 Month	18 Month	21 Month	24 Month
Clinical assessment
	Socio-demographic characteristics		√
	Psychological characteristics
		Personality	√						√			√
		Social support	√						√			√				√
		Stress-related status	√						√			√				√
		Outcomes of depression
		Depressive symptom	√	√	√	√	√	√	√	√	√	√	√	√	√	√
		Functional disability	√	√	√	√	√	√	√	√	√	√	√	√	√	√
		Suicidality	√	√	√	√	√	√	√	√	√	√	√	√	√	√
		Quality of life	√	√	√	√	√	√	√	√	√	√	√	√	√	√
Biological assessment
	Blood biomarker		√									√
	Salivary cortisol (cortisol study only)		√		√		√		√	√
	Electrocardiography		√									√
	Resting BP, body mass index		√		√		√		√	√	√	√	√	√	√	√
Treatment related assessment
	Antidepressants, dosage, duration		√	√	√	√	√	√	√	√	√	√	√	√	√	√
	Adverse events		√	√	√	√	√	√	√	√	√	√	√	√	√	√
	Withdrawal		√	√	√	√	√	√	√	√	√	√	√	√	√	√

MAKE BETTER: MAKE Biomarker discovery for Enhancing anTidepressants Treatment Effect and Response, BP: blood pressure