Psychiatry Investigation

Review Article

February 3, 2026

Evolving Alzheimer’s Disease Clinical Practice: Updated Diagnostic Criteria, Fluid Biomarkers, and Special Considerations for Anti-Amyloid Therapies

Hyun Woong Roh, Yoon Young Chang, Keun You Kim, So Yeon Jeon, Sheng-Min Wang, Eosu Kim, Jae-Nam Bae, Seung-Ho Ryu

Psychiatry Investig. 2026;23(2):183-200.

Objective This review overviewed the recent paradigm shifts in the diagnosis and management of Alzheimer’s disease (AD), emphasizing the 2024 Alzheimer’s Association (AA) revised criteria, advances in cerebrospinal fluid (CSF)...

Original Article

January 20, 2026

Occupational Stress and Anxiety Among Korean Employees: Moderated Mediation Model of Burnout and Grit

Sra Jung, Yoosuk An, Jeong Hun Yang, Junhyung Kim, Eun Soo Kim, Sang-Won Jeon, Sung Joon Cho

Psychiatry Investig. 2026;23(2):201-209.

Objective Although occupational stress is a major risk factor for high anxiety in employees, the specific mechanisms underlying this relationship are not sufficiently established. This study investigated an interpersonal model...

Original Article

January 20, 2026

Association Between Childhood Trauma and Somatization in a Clinical Sample: The Mediating Roles of Rumination, Cognitive Reappraisal, and Expressive Suppression

Mi-Sun Lee, Mimi Lee, Hyeong Beom Kim, Hyu Jung Huh

Psychiatry Investig. 2026;23(2):210-219.

Objective This study investigated the relationships among childhood trauma, somatization, depressive rumination, cognitive reappraisal, and expressive suppression among a clinical sample through a mediation model approach. Methods Outpatients (n=125) with a...

Original Article

January 20, 2026

The Gender Differences of Mediating Effect of Body Mass Index Between Perceived Control and Depressive Symptoms in Korean Workers

Yoosuk An, Sra Jung, Sang-Won Jeon, Junhyung Kim, Eun Soo Kim, Jeong Hun Yang, Sung Joon Cho

Psychiatry Investig. 2026;23(2):220-226.

Objective Depression impairs workplace productivity. Although obesity is associated with depression, findings differ across populations. Perceived control over stressors is an important psychological factor affecting both depression and weight regulation....

Original Article

January 20, 2026

The Impact of 5-HTTLPR Polymorphism on Depression and Lymphocyte Changes in Colorectal Cancer Patients Undergoing FOLFOX Chemotherapy

Seon-Young Kim, Min Jhon, Sung-Wan Kim, Seunghyong Ryu, Il-Seon Shin, Hee-ju Kang, Ju-Yeon Lee, Hyun-Jeong Shim, Jun Eul Hwang, Woo Kyun Bae, et al.

Psychiatry Investig. 2026;23(2):227-235.

Objective Depression could be related to immune function among cancer patients. The serotonin transporter gene has been reported for its associations with both depression and immune regulation. This study investigates...

Original Article

February 3, 2026

Clinical Features of Adults With Attention Deficit/Hyperactivity Disorder, Focusing on Their Adherence to Medication

Jae Kwang Shim, Soyoung Irene Lee, Shim-Gyeom Kim, Yujin Ko, HyunChul Youn, Jeewon Lee

Psychiatry Investig. 2026;23(2):236-241.

Objective The purpose of the present study was to examine the clinical features and medication adherence of the patients diagnosed with attention deficit/hyperactivity disorder (ADHD) in their adulthood. Methods The present...

Original Article

February 3, 2026

The Mediating Role of Rumination in the Relationship Between Childhood Trauma and the Severity of Major Depressive Disorder

Esra Yalım, Cansu Ünsal Mavi, Kamil Nahit Özmenler

Psychiatry Investig. 2026;23(2):242-248.

Objective It is widely accepted that childhood traumas increase the risk of major depressive disorder (MDD) in adulthood and contribute to the chronicity of the disorder. Various mediating factors are...

Original Article

February 3, 2026

Validation and Psychometric Properties of Behavioral Activation for Depression Scale in Older Adults

YoungImm Choi, YeonJoo Nam, Sungkun Cho, Tae Hui Kim

Psychiatry Investig. 2026;23(2):249-257.

Objective This study aimed to adapt and validate the Behavioral Activation for Depression Scale in older adults of Korea (BADS-OK), and to verify its factor structure, internal consistency, convergent and...

Original Article

February 3, 2026

Resting-State Functional Connectivity Changes Associated With Post-Traumatic Stress and Anxiety Symptoms in North Korean Refugees

Minjee Jung, Kyoung Jin Kim, Kyeong Jin Kim, Woo-Suk Tae, Byung-Joo Ham, Sin Gon Kim, Kyu-Man Han

Psychiatry Investig. 2026;23(2):258-269.

Objective North Korean refugees (NKRs) face substantial mental health challenges related to trauma during escape and resettlement, yet neurobiological research in this population is scarce. We examined resting-state functional connectivity...

Original Article

February 3, 2026

Quantitative Electroencephalography Analysis in Panic Disorder: Exploring the Neurophysiological Significance of High Beta Activity

Chang Hoon Park, Jun-Young Lee, Hee Yeon Jung, Seok-Im Lee, Sohee Oh, Jung-Seok Choi, Joon Hwan Jang, So Young Yoo

Psychiatry Investig. 2026;23(2):270-277.

Objective This study aimed to investigate the neurophysiological characteristics of panic disorder (PD) by analyzing quantitative electroencephalography (QEEG) data, with a particular focus on high beta activity. Methods In this retrospective...

Original Article

February 3, 2026

The Relationship Between Hopelessness and Childhood Traumas in Men With Methamphetamine Use Disorder: The Mediating Role of Perceived Social Support

Meltem Hazel Şimşek, Ulaş Korkmaz, Fatma Gül Helvacı Çelik

Psychiatry Investig. 2026;23(2):278-288.

Objective This study aims to investigate the effect of childhood trauma (CT) on the level of hopelessness in individuals diagnosed with methamphetamine use disorder (MUD) and the mediating role of...