Psychiatry Investigation

Is Richard Baxter’s Melancholia Still Relevant Today?: Comparative Network Structures of Depressive Symptoms in Asian Individuals With Guilt-Rich and Guilt-Free Depression: Hong Seok Oh, Junghyung Kim, Jungsoo Park, Kiwon Kim, Eunkyung Kim, Jaechang Lee, Tae Young Choi, Sung-Won Jung, Hyung-Jun Yoon, Hyun Soo Kim, Eunsoo Moon, Hyun-Ju Yang, Narae Jeong, Heechan Yoon, Tian-Mei Si, Roy Abraham Kallivayalil, Andi J. Tanra, Amir Hossein Jalali Nadoushan, Kok Yoon Chee, Afzal Javed, Kang Sim, Pornjira Pariwatcharakul, Takahiro A. Kato, Shih-Ku Lin, Naotaka Shinfuku, Norman Sartorius, Seon-Cheol Park; Psychiatry Investig. 2026;23(7):861-872. Published online June 16, 2026; DOI: https://doi.org/10.30773/pi.2025.0371; Full text PubReader ePub PDF

How Is the Loneliness Affected by Family and Friend Support in Adolescents With Depressive Disorder: The Mediating Role of Coping Strategies: Xiaoli Huan, Xuejun Li, Yuehua Cao, Xuan Lei, Wenzhao Chen, Yanni Wang, Yongjie Zhou; Psychiatry Investig. 2026;23(6):797-808. Published online June 8, 2026; DOI: https://doi.org/10.30773/pi.2025.0455; Full text PubReader ePub PDF

Glymphatic Dysfunction and Related Brain Structure Changes in Major Depressive Disorder: Effects of Glymphatic Function in Mediating Neuroinflammation: Daun Shin, Kyu-Man Han, Youbin Kang, Dorothee P. Auer, Woo Suk Tae, Byung-Joo Ham; Psychiatry Investig. 2026;23(5):644-657. Published online May 11, 2026; DOI: https://doi.org/10.30773/pi.2025.0456
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Bipolar Disorder Versus Unipolar Depressive Disorder in Female Psycho-Oncology Outpatients With Breast Cancer: Kyeong A Kang, C. Hyung Keun Park; Psychiatry Investig. 2026;23(5):597-604. Published online May 11, 2026; DOI: https://doi.org/10.30773/pi.2025.0386; Full text PubReader ePub PDF

Psychometric Properties of the Mixed State Severity Index for Patients With Mood Disorder: Woojae Myung, Hyeona Yu, Hyo Shin Kang, Daseul Lee, Junwoo Jang, Jakyung Lee, Joohyun Yoon, Yun Seong Park, Hyun A Ryoo, Ye Rim Kim, Kwang Ho Park, Chan Woo Lee, Yoonjeong Jang, Kimyoung Kim, Nara Lee, Sanghoon Hong, Hong-Hee Won, Tae Hyon Ha, Jungkyu Park; Psychiatry Investig. 2026;23(1):106-117. Published online January 7, 2026; DOI: https://doi.org/10.30773/pi.2025.0201; Full text PubReader ePub PDF Supplementary Materials

A Randomized Controlled Trial of Group-Based Acceptance and Commitment Therapy for Major Depressive Disorder: Sang Won Lee, Ho Seok Seo, Mina Choi, Seung Jae Lee; Psychiatry Investig. 2025;22(11):1300-1308. Published online November 12, 2025; DOI: https://doi.org/10.30773/pi.2025.0093
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Global Burden of Depressive Disorders, 1990–2021, During the COVID-19 Pandemic and Projections to 2050: A Global Burden of Disease Study 2021: Eunchae Lee, Jinyoung Jeong, Seohyun Hong, Sooji Lee, Jaehyun Kong, Hyeseung Lee, Dong Keon Yon; Psychiatry Investig. 2025;22(11):1277-1289. Published online November 12, 2025; DOI: https://doi.org/10.30773/pi.2025.0211
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Effects of Intranasal Oxytocin Across Various Depressive Disorders: Miao Wang, Shuaibiao Hou, Chaoyang Tian, Zhiyi Fu, Jing Jie; Psychiatry Investig. 2025;22(9):964-978. Published online August 14, 2025; DOI: https://doi.org/10.30773/pi.2024.0320
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The Association Between Childhood Trauma and Selective Serotonin Reuptake Inhibitor Treatment Outcomes in Adult Patients With Major Depressive Disorder: Yutong Deng, Wen Bian, Jingwen Sun, Lijun Liu, Shuzhe Zhou, Qi Liu, Tianmei Si, Jing Wang, Hongjun Tian, Kerang Zhang, Jing Wei, Gang Wang, Qiaoling Chen, Gang Zhu, Xueyi Wang, Nan Zhang, Xiaozhen Lv, Xin Yu; Psychiatry Investig. 2025;22(8):886-896. Published online July 31, 2025; DOI: https://doi.org/10.30773/pi.2024.0364
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Cytokine-Related Genes and Inflammatory Profiles as Potential Biomarkers in Major Depressive Disorder: Haein Oh, Na Yeong Kong, Sung-Won Jung, Hee-Cheol Kim, Shin Kim, Junho Kang, Hojun Lee; Psychiatry Investig. 2025;22(8):858-869. Published online July 31, 2025; DOI: https://doi.org/10.30773/pi.2025.0013
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Discriminative Accuracy of Affective Temperaments in Assessing Suicide Risk: Kyeong A Kang, Suyeon Lee, Seong Yoon Kim, C. Hyung Keun Park; Psychiatry Investig. 2025;22(7):796-805. Published online July 16, 2025; DOI: https://doi.org/10.30773/pi.2025.0036; Full text PubReader ePub PDF

Classification of Depressive Symptoms Among Bereaved Families of Sewol Ferry Disaster Victims Using Latent Profile Analysis: Yu-Ri Lee, Jinhee Hyun, Sunju Sohn, Jong-Sun Lee, Hyu Jung Huh, Kyonghwa Kang; Psychiatry Investig. 2025;22(6):650-659. Published online May 27, 2025; DOI: https://doi.org/10.30773/pi.2024.0272; Full text PubReader ePub PDF

Exploring the Correlation of Childhood Trauma With the Behavioral Activation and Inhibition System in Major Depressive Disorder and Bipolar I and II Disorders: Yoonjeong Jang, Sarah Soonji Kwon, Hyeona Yu, Daseul Lee, Joohyun Yoon, Chan Woo Lee, Yun Seong Park, Hyun A Ryoo, Yejin Park, Hyuk Joon Lee, Yeong Chan Lee, Hong-Hee Won, Tae Hyon Ha, Woojae Myung; Psychiatry Investig. 2025;22(6):620-631. Published online June 16, 2025; DOI: https://doi.org/10.30773/pi.2024.0247; Full text PubReader ePub PDF Supplementary Materials

Decoupled but Intertwined Association Between Dissociation and Depression: The Impact of Sleep and Gastrointestinal Symptoms: Yung-Chi Hsieh, Chui-De Chiu, Li-Shiu Chou, Ching-Hua Lin, Dian-Jeng Li; Psychiatry Investig. 2025;22(5):583-590. Published online May 15, 2025; DOI: https://doi.org/10.30773/pi.2024.0076; Full text PubReader ePub PDF Supplementary Materials

Cognitive Function as a Predictor of Short-Term Pharmacological Treatment Response in Major Depressive Disorder: Mediating Effect of Mentalization: Seon Hee Hwang, Myung Sun Kim, Byung Joo Ham; Psychiatry Investig. 2025;22(5):522-530. Published online May 15, 2025; DOI: https://doi.org/10.30773/pi.2024.0203
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