Increased Low-Density Lipoprotein Cholesterol Levels after 6 Months of Citalopram Treatment in Patients with Panic Disorder |
Hyun-Wook Cho, MD; and Bum-Hee Yu, MD, PhD |
Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
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Abstract |
<p class="MsoPlainText" style="word-spacing: 1; line-height: 150%; margin-top: 0; margin-bottom: 0" align="left"> <font size="2" face="HY중고딕">Objective</font> <font face="HY중고딕" size="2"> :
Panic disorder is associated with an increased cardiovascular risk. Furthermore, several studies reported increased cholesterol levels after treatment with selective serotonin reuptake inhibitors (SSRIs).
Methods
We examined the serum cholesterol levels in 21 panic disorder patients before and after 24 weeks of treatment with citalopram.
Results
The levels of serum low-density lipoprotein cholesterol (LDL-C) were significantly increased after the treatment, whereas there were no significant changes in the levels of serum total cholesterol, triglyceride and high-density lipoprotein cholesterol (HDL-C). Significant weight changes were observed as well.
Conclusions
Citalopram should be used with caution when panic patients have high risk of cardiovascular disorders. </span></font>
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Key words
Citalopram;Cholesterol;Panic disorder. |
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