Psychiatry Investigation

Original Article

September 13, 2018

Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43

Fang Shen, Wan-li Huang, Bao-ping Xing, Xiang Fang, Mei Feng, Chun-ming Jiang

Psychiatry Investig. 2018;15(10):919-925.

Objective Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR221/222. This study is to explore whether genistein could improve depression by altering...

Original Article

September 13, 2018

Gender-Specific Associations of Sensory Impairments with Depression and Cognitive Impairment in Later Life

Jiyoung Lyu, Hae-Young Kim

Psychiatry Investig. 2018;15(10):926-934.

Objective Sensory impairments, such as vision and hearing impairments, increase with age, and studies have shown that self-reported vision and hearing impairments are associated with adverse mental health outcomes in...

Original Article

October 11, 2018

Spatial Learning and Memory Using a Radial Arm Maze with a Head-Mounted Display

Hyunjeong Kim, Jin Young Park, Kwanguk (Kenny) Kim

Psychiatry Investig. 2018;15(10):935-944.

Objective A radial arm maze (RAM) is an essential tool for assessing spatial learning and memory. Although this tool is widely used to study deficits in spatial memory in animal...

Original Article

September 19, 2018

Assessment of Cognition in Schizophrenia Using Trail Making Test: A Meta-Analysis

Erna Laere, Shiau Foon Tee, Pek Yee Tang

Psychiatry Investig. 2018;15(10):945-955.

Objective The present meta-analysis aimed to analyze the cognitive performance of schizophrenia patients measured by Trail Making Tests (TMT) and the contribution of socio-demographic factors to cognitive impairments. Methods PubMed and...

Original Article

September 13, 2018

Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects

Miho Ota, Junko Matsuo, Noriko Sato, Toshiya Teraishi, Hiroaki Hori, Kotaro Hattori, Yoko Kamio, Norihide Maikusa, Hiroshi Matsuda, Hiroshi Kunugi

Psychiatry Investig. 2018;15(10):956-961.

Objective Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate...

Original Article

October 11, 2018

Mediating Effect of Internet Addiction on the Association between Resilience and Depression among Korean University Students: A Structural Equation Modeling Approach

Kwok Kei Mak, Jaeseung Jeong, Hye-Kyung Lee, Kounseok Lee

Psychiatry Investig. 2018;15(10):962-969.

Objective This study examined the mediating role of internet addiction in the association between psychological resilience and depressive symptoms. Methods 837 Korean university students completed a survey with items of demographic...

Original Article

October 11, 2018

Does Psychodrama Affect Perceived Stress, Anxiety-Depression Scores and Saliva Cortisol in Patients with Depression?

Lale Gönenir Erbay, İsmail Reyhani, Süheyla Ünal, Cemal Özcan, Tuba Özgöçer, Cihat Uçar, Sedat Yıldız

Psychiatry Investig. 2018;15(10):970-975.

Objective Little is known about the effects of psychodrama group therapy on the level of stress, anxiety and depression of the group members, and the biological markers of stress. The...

Original Article

October 11, 2018

Reliability and Validity of the Korean Version of Health Anxiety Questionnaire

Kyu-Sic Hwang, Seung-Ho Jang, Hye-Jin Lee, Sang-Yeol Lee

Psychiatry Investig. 2018;15(10):976-983.

Objective Health anxiety can be defined by concern about health in the absence of a pathology. The Health Anxiety Questionnaire (HAQ) based on the cognitive-behavioral model can be useful for...

Original Article

October 11, 2018

How Game Addiction Rates and Related Psychosocial Risk Factors Change Within 2-Years: A Follow-Up Study

Erkan Baysak, Fatma Duygu Kaya Yertutanol, Ilker Dalgar, Selçuk Candansayar

Psychiatry Investig. 2018;15(10):984-990.

Objective Prospective data of risky online gamers in Turkey is missing. Therefore, we aimed to investigate the change in gaming behaviors and addiction rates of Travian players within two years...

Original Article

October 11, 2018

Smart Stress Care: Usability, Feasibility and Preliminary Efficacy of Fully Automated Stress Management Application for Employees

Ji Hyun Baek, Jeong Hyun Kim, Sohee Oh, Ju Young Kim, Soyoung Baik

Psychiatry Investig. 2018;15(10):991-999.

Objective We developed a fully automated smartphone-based stress management application and explored its usability, potential feasibility, and preliminary efficacy for stress management in Korean employees. Methods Healthy employees working in large...

Original Article

October 11, 2018

Effects of 5HT1A Activation on Depression Profile Following 5-HT Depletion in Rats Lacking Social Attachment Since Weanling

Kuo-Jung Chang, Yu-Jung Chen, Jing-Yi Chung, Chen-Cheng Lin, Yia-Ping Liu

Psychiatry Investig. 2018;15(10):1000-1006.

Objective Post weanling isolation-reared (IR) rats are featured with depressive phenotype, yet its mechanism is not clearly defined particularly in terms of the involvement of central 5-HT1A receptors. The present...

Adult Guardianship in Korea: What Do Psychiatrists Need to Know? Hyun Kook Lim Psychiatry Investig. 2018;15(10):917-918. Perspective October 22, 2018 Full text PubReader ePub PDF	Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43 Fang Shen, Wan-li Huang, Bao-ping Xing, Xiang Fang, Mei Feng, Chun-ming Jiang Psychiatry Investig. 2018;15(10):919-925. Original Article September 13, 2018 Full text PubReader ePub PDF
Gender-Specific Associations of Sensory Impairments with Depression and Cognitive Impairment in Later Life Jiyoung Lyu, Hae-Young Kim Psychiatry Investig. 2018;15(10):926-934. Original Article September 13, 2018 Full text PubReader ePub PDF	Spatial Learning and Memory Using a Radial Arm Maze with a Head-Mounted Display Hyunjeong Kim, Jin Young Park, Kwanguk (Kenny) Kim Psychiatry Investig. 2018;15(10):935-944. Original Article October 11, 2018 Full text PubReader ePub PDF
Assessment of Cognition in Schizophrenia Using Trail Making Test: A Meta-Analysis Erna Laere, Shiau Foon Tee, Pek Yee Tang Psychiatry Investig. 2018;15(10):945-955. Original Article September 19, 2018 Full text PubReader ePub PDF	Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects Miho Ota, Junko Matsuo, Noriko Sato, Toshiya Teraishi, Hiroaki Hori, Kotaro Hattori, Yoko Kamio, Norihide Maikusa, Hiroshi Matsuda, Hiroshi Kunugi Psychiatry Investig. 2018;15(10):956-961. Original Article September 13, 2018 Full text PubReader ePub PDF
Mediating Effect of Internet Addiction on the Association between Resilience and Depression among Korean University Students: A Structural Equation Modeling Approach Kwok Kei Mak, Jaeseung Jeong, Hye-Kyung Lee, Kounseok Lee Psychiatry Investig. 2018;15(10):962-969. Original Article October 11, 2018 Full text PubReader ePub PDF	Does Psychodrama Affect Perceived Stress, Anxiety-Depression Scores and Saliva Cortisol in Patients with Depression? Lale Gönenir Erbay, İsmail Reyhani, Süheyla Ünal, Cemal Özcan, Tuba Özgöçer, Cihat Uçar, Sedat Yıldız Psychiatry Investig. 2018;15(10):970-975. Original Article October 11, 2018 Full text PubReader ePub PDF
Reliability and Validity of the Korean Version of Health Anxiety Questionnaire Kyu-Sic Hwang, Seung-Ho Jang, Hye-Jin Lee, Sang-Yeol Lee Psychiatry Investig. 2018;15(10):976-983. Original Article October 11, 2018 Full text PubReader ePub PDF Supplementary Material	How Game Addiction Rates and Related Psychosocial Risk Factors Change Within 2-Years: A Follow-Up Study Erkan Baysak, Fatma Duygu Kaya Yertutanol, Ilker Dalgar, Selçuk Candansayar Psychiatry Investig. 2018;15(10):984-990. Original Article October 11, 2018 Full text PubReader ePub PDF
Smart Stress Care: Usability, Feasibility and Preliminary Efficacy of Fully Automated Stress Management Application for Employees Ji Hyun Baek, Jeong Hyun Kim, Sohee Oh, Ju Young Kim, Soyoung Baik Psychiatry Investig. 2018;15(10):991-999. Original Article October 11, 2018 Full text PubReader ePub PDF	Effects of 5HT1A Activation on Depression Profile Following 5-HT Depletion in Rats Lacking Social Attachment Since Weanling Kuo-Jung Chang, Yu-Jung Chen, Jing-Yi Chung, Chen-Cheng Lin, Yia-Ping Liu Psychiatry Investig. 2018;15(10):1000-1006. Original Article October 11, 2018 Full text PubReader ePub PDF
Differences in High Dose Antipsychotic Prescriptions in Patients with Schizophrenia in Asian Countries/Areas: Findings from the REAP-AP Study Yong Chon Park, Shu-Yu Yang, Mian-Yoon Chong, Shigenobu Kanba, Norman Sartorius, Naotaka Shinfuku, Chay-Hoon Tan, Seon-Cheol Park Psychiatry Investig. 2018;15(10):1007-1008. Correspondence October 22, 2018 Full text PubReader ePub PDF